Effect of hesperetin on chaperone activity in selenite-induced cataract

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چکیده

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Effect of hesperetin on chaperone activity in selenite-induced cataract

BACKGROUND Chaperone activity of α-crystallin in the lens works to prevent protein aggregation and is important to maintain the lens transparency. This study evaluated the effect of hesperetin on lens chaperone activity in selenite-induced cataracts. METHODOLOGY Thirteen-day-old rats were divided into four groups. Animals were given hesperetin (groups G2 and G4) or vehicle (G1 and G3) on Days...

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Hesperetin prevents selenite-induced cataract in rats

PURPOSE This study investigated the ability of hesperetin, a natural flavonoid, to prevent selenite-induced cataracts in a rat model. METHODS Animals were divided into four treatment groups: G1 (control group), G2 (hesperetin-treated group), G3 (selenite-induced cataract group), and G4 (hesperetin-treated selenite cataract group). Animals in the G1 and G3 groups were injected with vehicle alo...

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Effect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats

Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...

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Effect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats

Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...

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ژورنال

عنوان ژورنال: Open Medicine

سال: 2016

ISSN: 2391-5463

DOI: 10.1515/med-2016-0035